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Got Histamine Issues? Check Your Estrogen.

Got histamine problems? 🤧 Check your estrogen.
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In my “histamine: the ultimate hormone of alarm” post, I talked about how nutrient deficiencies can be a huge driver of histamine intolerance. Hormones can be a big one too.
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Histamine and estrogen potentiate (increase) each other. Estrogen activates mast cells to release histamine. Histamine stimulates estrogen secretion from the granulosa cells of the ovary. It creates a vicious cycle.
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Histamine ➡️ more estrogen
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Estrogen ➡️ more histamine
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Of course, minerals run enzymes which run hormones. The plot thickens when you can also understand that estrogen and iron potentiate each other too (another vicious cycle). And iron depletes copper, one of the main minerals needed to create the Diamine Oxidase (DAO) enzyme that clears histamine.
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On the birth control pill, my allergies were horrendous, which makes sense because I was estrogen-dominant and iron-toxic.
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To truly quell histamine intolerance, you must break the cycle(s). And it usually requires a holistic approach.
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A few tips:
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〰️Work on reducing estrogen exposure, like xenoestrogens that you come in contact with or phytoestrogens that you consume. Especially PUFAs, which turn on the production of more mast cells and increase histamine leakage.
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〰️Eat balanced meals at a frequency right for you to keep detox pathways up.
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〰️Fight for your progesterone, which has antihistamine effects. Nourish yourself with nutrient-dense foods at the right frequency to reduce stress and boost its production.
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〰️Make sure you’re getting enough Copper, Vitamin B6, Vitamin C and Magnesium daily.
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〰️Vitamin E can also prevent the degranulation of mast cells, which can help break the cycle as well.
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Not medical advice.

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This is not medical advice. Always consult your healthcare professional before pursuing any changes to your personal healthcare regime.

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References

Kresser, C. (2019). Could Your Histamine Intolerance Really Be Mast Cell Activation Disorder?. Retrieved from: https://chriskresser.com/could-your-histamine-intolerance-really-be-mast-cell-activation-disorder/comment-page-4/.

Peat, R. (1997). From PMS to Menopause. Eugene, OR.

Peat, R. (2012). Serotonin, depression, and aggression: The problem of brain energy. Retrieved from: https://raypeat.com/articles/articles/serotonin-depression-aggression.shtml.

Peat, R. Not the "female hormone," but the shock hormone. Retrieved from: http://raypeat.com/articles/hormones/h1.shtml.

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Remember: this post is for informational purposes only and may not be the best fit for you and your personal situation. It shall not be construed as medical advice. The information and education provided here is not intended or implied to supplement or replace professional medical treatment, advice, and/or diagnosis. Always check with your own physician or medical professional before trying or implementing any information read here. While the owner of this website tries to keep the information up to date, there may be things that are out-of-date and out of their control.