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Got histamine probs? It might be your gut.

allergy balancing hormones gut histamine minerals multi-vitamins

Got histamine intolerance? Keep reading.

As you’ve learned from my previous posts on histamine, there are many things that can influence our ability to clear it, including estrogen and vitamin and mineral levels.

One very overlooked factor when it comes to histamine intolerance? Mucosal barrier function.

The mucosal barrier lines the digestive tract and protects the internal (bloodstre@m) from the external (toxins). It’s primary job is to let good things in, like properly digested nutrients, and keep bad things out, like p@thogens.

DAO, the enzyme that breaks down histamine, is made in the crypts of the mucosal barrier.

There are many things that can compromise this barrier, but when this happens, the production of the DAO enzyme becomes compromised too. Histamine builds up and then we experience histamine intolerance symptoms.

This is why gut health is such an important piece of solving histamine intolerance once and for all.

Where to go from here?

⤳Get the vitamins and minerals that support DAO production and discourage histamine production (see my posts on this)

⤳Support detoxification pathways for proper estrogen elimination (see my post on this)

⤳Remove gut-irritating foods (this will vary from person-to-person)

⤳Consume gut-supportive foods, including collagen and gelatin-rich foods, organ meats, Vitamin Ⓒ-rich foods (as can be tolerated)

⤳Make sure your bowel movements are regular and satisfying

⤳Manage stress

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Not medical advice.
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This is not medical advice. Always consult your healthcare professional before pursuing any changes to your personal healthcare regime.

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References

Camilleri, M. Lyle, B.J. Madsen, K.L. Sonnenburg, J. Verbeke, K. Wu, G.D. (2019). Role for diet in normal gut barrier function: developing guidance within the framework of food-labeling regulations. Retrieved from: https://journals.physiology.org/doi/full/10.1152/ajpgi.00063.2019.

Sebe, M. Tsutsumi, R. Yamaguchi, S. Horikawa, Y.T. Harada, N. Oyama, T. Kakuta, N. Tanaka, K. Tsutsumi, Y.M. Nayaka, Y. Sakaue, H. (2016). The synergystic effects of omega-3 fatty acids against 5-fluorouracil-induced mucosal impairment in mice. Retrieved from: https://bmcnutr.biomedcentral.com/articles/10.1186/s40795-016-0057-7.

Small Intestine epithelial Barrier Function Is Compromised in Pigs with Low Feed Intake at Weaning  Spreeuwenberg, M.A.M. Verdonk, J.M.A.J. Gaskins, H.R. Verstegen, M.W.A. (2001). Small Intestine Epithelial Barrier Function Is Compromised in Pigs with Low Feed Intake at Weaning. Retrieved from: https://academic.oup.com/jn/article/131/5/1520/4686925.

Tufarelli, V. (2021). Poultry Nutrition. Retrieved from: MDPI AG.Wollin, A. Navert, H. Bounos, G. (1981). Effect of Intestinal Ischemia on Diamine Oxidase Activity in Rat Intestinal Tissue and Blood. Retrieved from: https://www.gastrojournal.org/article/0016-5085(81)90725-3/pdf.

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Remember: this post is for informational purposes only and may not be the best fit for you and your personal situation. It shall not be construed as medical advice. The information and education provided here is not intended or implied to supplement or replace professional medical treatment, advice, and/or diagnosis. Always check with your own physician or medical professional before trying or implementing any information read here. While the owner of this website tries to keep the information up to date, there may be things that are out-of-date and out of their control.