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40-60% of the population may not be able to properly convert Folic Acid.

folate folic acid mthfr nutrients preconception ttc

#MTHFR...we hear about it so often, but what’s the deal?

Well, the truth is that everyone has MTHFR! 🤯

MTHFR actually refers to the enzyme methyltetrahydrofolate reductase, which has several important roles, including a big one in Folate (Vitamin B9) metabolism.

What most people mean when they say “I have MTHFR” is that they have a polymorphism aka one or more variations in DN@ sequence. This means they can have less enzymatic MTHFR activity and thus, have issues with Folate metabolism, especially when it comes to converting synthetic Folic Acid.

That said, it’s not just a few of us that have this issue. It’s quite a big chunk!

“About 40% to 60% of the population has genetɪc polymorphisms that impair the conversion of supplemental folic acid to its active form, l-methylfolate.” (Bell)

So in short, for about ½ of the population, Folic Acid isn’t all it’s cracked up to be. And because Folate is so important to optimal fertility and building a healthy baby, it can be important to figure out if you’re one of the 40-60% that has one of these MTHFR mutations.

Want to learn more? Discover which lab tests to get, which foods to eat, which supplements to take and so much more in my new course Conscious Conception, which is officially LIVE! Use code LAUNCH100 for $100 OFF today until Wednesday, 7/28 @ midnight ET.

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Not medical advice.

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This is not medical advice. Always consult your healthcare professional before pursuing any changes to your personal healthcare regime.

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References

Greenberg, J.A. Bell, S.J. (2011). Multivitamin Supplementation During Pregnancy: Emphasis on Folic Acid and l-Methylfolate. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250974/.

 

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Remember: this post is for informational purposes only and may not be the best fit for you and your personal situation. It shall not be construed as medical advice. The information and education provided here is not intended or implied to supplement or replace professional medical treatment, advice, and/or diagnosis. Always check with your own physician or medical professional before trying or implementing any information read here. While the owner of this website tries to keep the information up to date, there may be things that are out-of-date and out of their control.